Proteus OX2, OX19 & OXK antigen suspensions employed in the Weil-Felix test are used for diagnosis of Rickettsial infection. Rickettisal infection is an arthropod associated infection transmitted by ticks, mites, lice, or fleas to humans as accidental host. Antigen suspension of Proteus OX19 reacts strongly with sera of patients with typhus group and spotted fever group. Proteus OX2 reacts strongly with sera of patients with spotted fever, while the Proteus OXK antigen suspension reacts strongly with sera of patients with scrub typhus.
